Clinical effect observation of anatomical retroperitoneoscopic adrenalectomy in 56 patients with adrenal tumors
10.3760/cma.j.cn311847-202200302-00079
- VernacularTitle:解剖性后腹腔镜切除术治疗肾上腺肿瘤患者56例临床疗效观察
- Author:
Xuesong GAO
1
;
Zhuomin JIA
1
;
Yi WANG
1
;
Yubo ZHAO
1
;
Xiyou WANG
1
;
Yansheng XU
1
;
Dan SHEN
1
Author Information
1. 解放军总医院第三医学中心泌尿外科临床医学部，北京 100039
- Publication Type:Journal Article
- Keywords:
Adrenal tumors;
Anatomical retroperitoneoscopic adrenalectomy;
Inflammatory factors;
Electrolytes;
Complication
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2022;29(3):384-388
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the applicable effect of anatomical retroperitoneoscopic adrenalectomy in treating patients with adrenal tumors.Methods:A total of 112 patients with adrenal tumors admitted to the Department of urology of The Third Medical Center of Chinese PLA General Hospital from January 2016 to January 2021 were selected as research subjects，and they were divided into control group and study group according to the double-blind method，with 56 cases in each group. The patients in the control group were treated with laparoscopic transabdominal adrenalectomy，while the patients in the study group were treated with anatomical retroperitoneoscopic adrenalectomy. The clinical indicators of the two surgical methods were compared. Before and six hours after surgery，the serum levels of inflammatory factors including interleukin-6（IL-6），interleukin-1β（IL-1β），and hypersensitive C-reactive protein（hs-CRP）were detected by enzyme-linked immunosorbent assay（ELISA），and the electrolytes such as Na +，K +，and bicarbonate（HCO 3-）were detected by the America-made Medica electrolyte analyzer. The prognosis and incidence of complications in the two groups were observed. Results:Compared with the control group，the time spent in operation，the time spent for drainage tube placement and gastrointestinal function recovery，and hospital stay were all shorter in the study group（ P < 0.05 or P < 0.01）. After surgery，the serum levels of IL-6，IL-1β，and hs-CRP in the study group were significantly lower than those in the control group，and the levels of Na + and HCO 3- in the study group were also lower than those in the control group，while the K + level was higher than that in the control group，all with statistically significant differences（ P < 0.05 or P < 0.01）. The incidence of complications in the study group［3.57%（2/56）］was significantly lower than that in the control group［（14.29%（8/56）］，with statistically significant difference（ P < 0.05）. No recurrence or metastasis occurred in the two groups during the six-month follow-up after surgery. Conclusion:Anatomical retroperitoneoscopic adrenalectomy can better reduce the surgery trauma to patients with adrenal tumors，lessen the impact on the internal environment of patients，effectively promote the postoperative rehabilitation process，and has higher safety.
