Application of patient-derived organoid in precision medicine of urological malignancy
10.3760/cma.j.cn112330-20230316-00082
- VernacularTitle:患者来源类器官在泌尿系统肿瘤精准治疗中的应用
- Author:
Meijing WU
1
;
Xinrong LIAN
;
Yueping LIU
Author Information
1. 北京协和医学院，北京 100730
- Publication Type:Journal Article
- Keywords:
Prostatic neoplasms;
Urinary bladder neoplasms;
Kidney neoplasms;
Organoids;
Precision medicine
- From:
Chinese Journal of Urology
2024;45(11):877-880
- CountryChina
- Language:Chinese
-
Abstract:
Patient-derived organoid is an emerging in vitro model in tumor research, highly preserving intratumoral and intertumoral heterogeneity, monitoring patients’ response to drugs and other therapies, and guiding precision medicine choice for tumor treatment. This review described the application of patient-derived organoid in drug sensitivity test, cancer biomarkers, validation of new therapies in prostate cancer, bladder cancer, and renal cancer, exhibiting the role of patient-derived organoid in clinical tumor research.
