Long term prognosis of patients with localized renal cell carcinoma undergoing laparoscopic partial nephrectomy
- VernacularTitle:局限性肾癌患者腹腔镜肾部分切除术后长期预后的研究
- Author:
Chunlei XUE
1
;
Xuan ZHANG
1
;
Hui WANG
1
Author Information
- Publication Type:Journal Article
- Keywords: localized renal cell carcinoma; laparoscopic partial nephrectomy; long term; prognosis
- From: China Journal of Endoscopy 2025;31(3):20-27
- CountryChina
- Language:Chinese
- Abstract: Objective To analyze the related factors of long-term prognosis of patients with localized renal cell carcinoma after laparoscopic partial nephrectomy.Method Clinical data of 110 patients with localized renal cell carcinoma who underwent laparoscopic partial nephrectomy from January 2020 to January 2021 were retrospectively analyzed.According to whether the patients died within 3 years after operation,they were divided into death group(n=19)and survival group(n=91).The related factors of long-term prognosis of the two groups were compared.Results Compared with the survival group,the proportion of hyperlipidemia,diabetes,hypertension,sarcomatoid differentiation,clear cell type,T1b～T3a stage and American Society of Anesthesiologists(ASA)grade Ⅲ～Ⅵ in the death group increased(P＜0.05),the maximum diameter of tumor increased(P＜0.05),score of Mayo adhesive probability(MAP)and perirenal fat density increased(P＜0.05),the operation time and indwelling drainage tube time prolonged(P＜0.05),and the levels of blood urea nitrogen(BUN),creatinine(Cr),hypersensitive C-reactive protein(Hs-CRP),total cholesterol(TC)and microalbuminuria(MAU)increased(P＜0.05).Sarcomatoid differentiation(OR=1.737,95％CI:1.074～2.807),T stage of T1b～T3a(OR=1.627,95％CI:1.182～2.240)and level of Cr≥91.27 μmol/L(OR=1.923,95％CI:1.064～3.476)were risk factors for long-term prognosis of patients with localized renal cell carcinoma after laparoscopic partial nephrectomy(P＜0.05).Conclusion The mortality rate of patients with localized renal cell carcinoma within 3 years after laparoscopic partial nephrectomy is high.Sarcomatoid differentiation,T stage of T1b～T3a and level of Cr ≥ 91.27 μmol/L are related to the long-term prognosis of patients with localized renal cell carcinoma after laparoscopic partial nephrectomy.Clinical interventions could be taken for high-risk patients.
