Comparative study of prodromal symptoms between bipolar disorder and recurrent major depressive disorder
10.3760/cma.j.issn.1006-7884.2015.05.002
- VernacularTitle:双相障碍与复发性抑郁障碍患者前驱症状临床特点分析
- Author:
Yanping DUAN
1
;
Yanhong LIU
;
Lin CHEN
;
Chao CHEN
;
Ronghuan JIANG
;
Yuqing SONG
;
Tianmei SI
Author Information
1. 中国医学科学院北京协和医学院北京协和医院心理医学科
- Publication Type:Journal Article
- Keywords:
Bipolar disorder;
Depressive disorder;
Prodromal symptoms
- From:
Chinese Journal of Psychiatry
2015;48(5):260-265
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the differences of prodromal symptoms between bipolar disorder (BD) and recurrent major depressive disorder (RMDD).Methods We used the Bipolar Prodrome Symptom Interview and Scale-Retrospective to investigate 74 BD patients and 37 RMDD patients,which included open questions and semi-structured questions about the 39 prodromal symptoms to the first full depressive episode.Results (1) Most of BD patients (91.9％,68/74) and RMDD patients (97.3％,36/37) could recognize their prodromal symptoms.(2) BD patients reported more psychotic symptoms than RMDD patients (t=-3.761,P=0.001).(3) Compared with RMDD patients,more BD patients reported prodromal symptoms,overly cheerful/happy/on top of the world(16 cases (21.6％,16/74) vs.2 cases (5.4％,2/37),x2=5.269,P=0.022),overly talkative (19 cases (25.7％,19/74) vs.3 cases (8.1％,3/37),x2=5.370,P=0.020),racing thoughts or jumping from one thought to another (17 cases (23.0％,17/74) vs.3 cases (8.1％,3/37),x2=4.168,P=0.041),extremely energetic or active (18 cases (24.3％,18/74) vs.1 cases (2.7％,1/37),x2=8.777,P=0.003),overly self confident (14 cases (18.9％,17/74)vs.0,x2=8.514,P=0.002),and frequent mood swings/lability (38 cases (51.4％,38/74) vs.8 cases (24.3％,8/37),x2=10.537,P=0.001),and these symptoms were more likely to be a part of the bipolar prodromal symptoms.Conclusions BD patients and RMDD patients represent different prodromal symptoms,which could promote early identification and early intervention of BD.
