Progress of research into the zebrafish(Danio rerio)depression model
10.3969/j.issn.1005-4847.2025.02.013
- VernacularTitle:模式生物斑马鱼作为抑郁模型的研究进展
- Author:
Biyu GUO
1
;
Huiluan YANG
;
Yifan CHEN
;
Xiaomi YANG
;
Zheng YAO
;
Yu MAO
Author Information
1. 云南中医药大学基础医学院,昆明 650500
- Publication Type:Journal Article
- Keywords:
zebrafish;
depression;
animal model of disease
- From:
Acta Laboratorium Animalis Scientia Sinica
2025;33(2):275-287
- CountryChina
- Language:Chinese
-
Abstract:
The zebrafish is characterized by its rapid reproductive cycle,transparent embryonic body in the early developmental stages,high genetic and physiological homology with humans,and low breeding costs.These advantages make it a valuable tool that complements mammalian models of depression.The zebrafish has emerged as a promising model organism for studying mental illnesses owing to its unique biological characteristics and the diverse method available for establishing depression models using this species.This article aims to provide a comprehensive review of zebrafish depression model establishment method,evaluation criteria,advantages,and limitations.
