Correlation between triglyceride-glucose index and hyperuricemia in males with normal fasting blood glucose levels
- VernacularTitle:空腹血糖正常的成年男性甘油三酯-葡萄糖指数与高尿酸血症相关性的研究
- Author:
Jing XUE
1
;
Xiaowei WEI
1
;
Suying XIA
1
;
Weibo ZHAO
1
;
Lintao SHI
1
;
Jinyi SHI
1
;
Haiying JIA
1
;
Yueying YANG
1
;
Xiao YANG
1
;
Aihong WANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Hyperuricemia; Triglyceride-glucose index; Male
- From: Chinese Journal of Diabetes 2025;33(3):205-209
- CountryChina
- Language:Chinese
- Abstract: Objective To explore the correlation between triglyceride-glucose(TyG)index and hyperuricemia in men with normal fasting blood glucose(FPG)levels.Methods A total of 309 men with normal FPG who participated in a health examination at the Ninth Medical Center of the People's Liberation Army General Hospital in April 2024 were enrolled in this study.All the subjects were divided into the normal uric acid(NUA,n=218)group and the hyperuricemia(HUA,n=91)group according to serum uric acid(SUA)levels.Results Scr,TG,weight,SBP,DBP,BMI,ALT,AST,γ-GGT,and TyG index were higher in the HUA group than in the NUA group(P<0.05).Pearson and Spearman correlation analysis showed that SUA were positively correlated with Scr,eGFR,TG,weight,SBP,DBP,BMI,ALT,AST,γ-GGT and TyG(P<0.05),and negatively correlated with HDL-C(P<0.05).Logistic regression analysis showed that after adjusting for confounding factors,TyG index remained an important influencing factor for HUA.ROC curve analysis showed that the area under the ROC curve of TyG index predicting hyperuricemia in men with normal FPG was 0.665,with an cutoff value of 8.45.Conclusions TyG index in men with normal FPG are influencing factors for hyperuricemia,indicating that hyperuricemia has a close association with insulin resistance,and is an important component of metabolic syndrome.
