Research Progress of Amnesia Mild Cognitive lmpairment Caused by Long-term Negative Emotional Accumulation and Liver Failing to Govern Conveyance and Dispersion from the Perspective of Cognitive Flexibility
- VernacularTitle:从认知灵活性探讨长期负性情绪积累肝失疏泄致遗忘型轻度认知功能障碍的研究进展
- Author:
Zhongpeng QIN
1
;
Xianghong ZHAN
1
;
Lei HUO
1
Author Information
- Publication Type:Journal Article
- Keywords: Long-term negative emotional accumulation; Liver failing to govern conveyance and dispersion; Amnesia mild cognitive impairment(aMCI); Cognitive flexibility; Soothing liver-qi stagnation therapy
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2025;27(3):752-761
- CountryChina
- Language:Chinese
- Abstract: Rapid brain aging has become a social and medical problem to be solved urgently,among which amnesia mild cognitive impairment(aMCI)has attracted much attention because it is more likely to develop into Alzheimer's disease(AD)dementia.Many studies at home and abroad have reported that executive function decline is the initiating factor,key damage and sensitive index of cognitive aging,and long-term negative emotional accumulation and liver failing to govern conveyance and dispersion is an important risk factor for aMCI.Soothing liver-qi stagnation therapy can improve the overall cognitive function of aMCI patients,but the above mechanisms need to be further studied and explained.This paper focuses on the cognitive flexibility level of early sensitive components of cognitive decline and one of the core components of executive function,and summarizes the pathogenesis,risk factors,sensitive indicators,event-related potentials and eye tracking techniques of aMCI,and focuses on the effects and research progress of long-term negative emotional accumulation and liver failing to govern conveyance and dispersion on aMCI and cognitive flexibility.The purpose of this study is to provide reference and reference for the intervention and treatment of emotional pathogenesis in patients with aMCI,and to provide new perspectives,methods and ideas for the prevention and treatment of diseases with excessive cognitive decline in traditional Chinese medicine.
