Research progress of inhibition of NOD-like receptor protein 3 inflammasome activation for the treatment of diabetic cardiomyopathy
10.3969/j.issn.1006-6187.2025.03.013
- VernacularTitle:抑制NOD样受体蛋白3激活与糖尿病心肌病治疗的研究进展
- Author:
Lin AI
1
;
Dandan HAO
Author Information
1. 024000 赤峰学院教务处
- Publication Type:Journal Article
- Keywords:
Diabetic cardiomyopathy;
NOD-like receptor protein 3 inflammasome;
Pyroptosis;
Cardioprotective effects
- From:
Chinese Journal of Diabetes
2025;33(3):227-232
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic cardiomyopathy(DCM)is a serious complication of diabetes mellitus(DM).Recent studies have reported that the NOD-like receptor protein 3(NLRP3)inflammasome activation-mediated pyroptosis aggravates the formation and development of DCM.This review summarizes the mechanism of action of NLRP3 inflammasome in the development of DCM,and focus on the potential effects of targeted inhibition of NLRP3 inflammasome activation in the treatment of DCM.
