Discussion on the Intestinal Immune Mechanism and Clinical Diagnosis and Treatment of Hashimoto Thyroiditis Based on"Wood Depression and Earth Stagnation"
10.19879/j.cnki.1005-5304.202505232
- VernacularTitle:基于"木郁、土壅"探讨桥本甲状腺炎的肠道免疫机制及临床辨治
- Author:
Guijie WANG
1
;
Yukun WU
;
Zongliang YU
;
Zhenzhen QIAN
;
Jianxin WANG
;
Rui GAO
Author Information
1. 中国中医科学院西苑医院,北京 100091;中国中医科学院研究生院,北京 100700
- Publication Type:Journal Article
- Keywords:
Hashimoto thyroiditis;
wood depression;
earth stagnation;
intestinal immunity
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(11):172-176
- CountryChina
- Language:Chinese
-
Abstract:
Hashimoto thyroiditis(HT)is one of the most common autoimmune diseases."Wood depression and earth stagnation"is its important pathogenesis.Liver depression and qi stagnation,wood depression multiplies the earth,spleen deficiency and earth stagnation,phlegm and blood stasis intermingle,resulting in wood depression and earth stagnation.Or middle-earth stagnation insults wood in turn,liver yang deficiency,wood depression,and failure to disperse and discharge,resulting in earth stagnation and wood depression.It may be related to the intestinal immune mechanism in modern medical study.Based on the theory of"wood depression and earth stagnation",this article discussed the pathogenesis of HT from the perspective of wood depression and imbalance of microbe-gut-brain axis,earth stagnation and dysbiosis of intestinal flora,damage to the intestinal barrier,and proposed the treatment principles,i.e.,"disperse stagnated liver qi for relieving qi stagnation,ascend yang and regulate qi""eliminate stagnation and remove turbidity,invigorate spleen and restore normal movement",which could provide the ideas for mechanism research and clinical treatment of HT.
