Clinical study on the effect of hyperbaric oxygen intervention time on GCS and FIM scores in patients following traumatic brain injury
10.3760/cma.j.issn.1009-6906.2015.01.012
- VernacularTitle:颅脑外伤后高压氧介入时间对患者格拉斯哥昏迷量表评分和功能独立性评定评分影响的临床研究
- Author:
Fang YU
1
;
Shuo GU
1
;
Aiping LI
1
;
Kun LOU
1
;
Xiaomin DONG
1
Author Information
1. 南京军区杭州疗养院全军创伤康复中心,杭州,310007
- Publication Type:Journal Article
- Keywords:
Hyperbaric oxygen;
Rehabilitation;
Intervention time;
Functional independent measure;
Glasgow Coma Score
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2015;22(1):41-44
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of hyperbaric oxygen intervention time on Glasgow Coma Score (GCS) and functional independent measure (FIM) scores in patients following traumatic brain injury,so as to provide clinical evidence for optimal intervention time in the comprehensive rehabilitation of those patients.Methods There were 130 patients with moderate or severe traumatic brain injury (TBI),who were divided according to different injury time into 4 groups:the control group (n =25),the HBO group 1 (TBI ＜ 15 d) (n =40),the HBO group 2 (TBI time of 15 to 30 d) (n =40) and the HBO group 3 (TBI ＞ 30 d) (n =25).The patients in all the groups received drug therapy and rehabilitation treatment measures.On the basis of the above routine treatment,the patients in all the HBO groups were treated with HBO for a total of 40 sessions.Therapeutic efficacy was assessed by using GCS and FIM scores performed respectively at day one,day 30 and day 60.Results Statistical significance could be noticed in all the TBI groups in GCS and FIM scores performed at day 30 and day 60(P ＜0.01).For HBO group 1 and group 2,statistical differences could be seen in GCS scores detected at day 60 (13.36 ± 3.06,13.66 ± 1.42,11.83 ± 3.57),as compared with those of the control group(P ＜ 0.05).For HBO group 1 and group 2,statistical differences could also be seen in FIM scores detected respectively at day 30 and day 60,as compared with those of the control group (P ＜ 0.05).Variance in the scores of GCS and FIM was:group 1 was greater than group 2,group 2 was greater than group 3 and group 3 was greater than the control group.Conclusions Different HBO intervention time seemed to have some effect on the improvement of GCS and FIM scores in patients with traumatic brain injury.On the whole,treatment results indicated that the therapeutic effects for the HBO group 1 were superior to those for the HBO group 2,and the therapeutic effects for the HBO group 2 were superior to those for the HBO group 3.
