Chemical constituents from dichloromethane fraction of Dalbergia odorifera heartwood
10.3969/j.issn.1001-1528.2025.10.019
- VernacularTitle:降香黄檀心材二氯甲烷部位化学成分研究
- Author:
Wei-xin XU
1
;
Qing ZHU
;
Xing DAI
;
Lan-ying CHEN
;
Rong-hua LIU
Author Information
1. 江西中医药大学药学院,江西南昌 330004;江西中医药大学中药药效物质基础江西省重点实验室,江西南昌 330004
- Publication Type:Journal Article
- Keywords:
Dalbergia odorifera T.Chen;
heartwood;
dichloromethane fraction;
chemical constituents;
isolation and identification
- From:
Chinese Traditional Patent Medicine
2025;47(10):3297-3305
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the chemical constituents from dichloromethane fraction of Dalbergia odorifera T.Chen heartwood.METHODS Separation and purification were performed using silica gel,Sephadex LH-20,thin-layer chromatography,and semi-preparative HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Twenty-four compounds were isolated and identified as 7,2′-dihydroxy-4′-methoxy-isoflavanol(1),vanillin(2),2,2′-oxybis-(1,4-di-tert-butylbenzene)(3),7-hydroxy-6-methoxyflavone(4),sativan(5),5-hydroxy-4′,7-dimethoxyisoflavone(6),2-hydroxy-4,4′-dimethoxychalcone(7),7,2′,3′,4′-tetramethoxydihydroisoflavone(8),2,4,2′-trihydroxy-4′-methoxybenzil(9),ethyl-3-hydroxy-3-phenyl-2-propenoate(10),6,7-dimethoxy-2,3-dihydr-ochromen-4-one(11),sophorophenolone(12),apocynin(13),ethyl-2,4-dihydroxybenzoate(14),ethylparaben(15),methyl-2,4-dihydroxybenzoate(16),5,7-dihydroxy-6-methoxyflavanone(17),7-hydroxyflavanone(18),mimosifoliol(19),7-hydroxy-4′-methoxyisoflavane(20),virolane(21),5-hydroxy-7-methoxychromone(22),3-hydroxyl-5-methoxy-stilbene(23),2′,4′-dihydroxydihydrochalcone(24).CONCLUSION Compound 8 is new natural product,2-6,15,17-18 are isolated from this plant for the first time,7,9-14,16,20-24 are first isolated from genus Dalbergia.
