Investigation of hospital-acquired pulmonary mucormycosis caused by Cunninghamella bertholletiae in a child and its prevention and control
10.11816/cn.ni.2025-250831
- VernacularTitle:一例儿童灰色小克银汉霉肺毛霉菌病医院感染的调查与防控
- Author:
Jieling LIU
1
;
Qiaoling TIAN
;
Huarui XIAO
;
Lingling XIE
;
Yanjie XIA
;
Xue WANG
;
Xiaodong GAO
Author Information
1. 香港大学深圳医院感染性疾病医学部院感科,广东 深圳 518000
- Publication Type:Journal Article
- Keywords:
Cunninghamella bertholletiae;
Pulmonary mucormycosis;
Invasive fungal infection;
Infection preven-tion and control
- From:
Chinese Journal of Nosocomiology
2025;35(18):2800-2805
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE T o explore the prevention and control measures for the hospital-acquired pulmonary mu-cormycosis caused by Cunninghamella bertholletiae.METHODS One case of patient with pulmonary mucormyco-sis caused by Cunninghamella bertholletiae who was treated in pediatric intensive care unit(PICU)of a three-A general hospital was enrolled in the study,the process of clinical diagnosis and treatment was summarized.A ret-rospective survey regarding four aspects including people,machine,materials and environment was conducted.The related factors leading to the hospital-acquired infections in the patient were analyzed.RESULTS The child was diagnosed with severe aplastic anemia and underwent hematopoietic stem cell transplantation,the child was treated with various invasive procedures during the treatment period and was infected with pulmona-ry mucormycosis caused by the rare Cunninghamella bertholletiae.The occurrence of the pulmonary mucormyco-sis was associated with the poor management of medical textile,insufficient environmental cleaning and disinfec-tion and nonstandard invasive procedures.CONCLUSIONS The Cunninghamella bertholletiae infection is less com-mon,but the risk of death is high.It is necessary for the medical institutions to complete the prevention and con-trol measures and intensify the health care workers'capabilities in identification of the pathogenic fungus so as to reduce the incidence of pulmonary mucormycosis caused by the pathogen.
