Exploring the Pathogenesis Connotation of Wei-Qi-Ying-Xue Transmission in Acute Pancreatitis from a Metabolic Perspec-tive
10.14148/j.issn.1672-0482.2025.0300
- VernacularTitle:从代谢紊乱探讨急性胰腺炎卫气营血传变病机内涵
- Author:
Qi QIU
1
;
Chenxia HAN
;
Tao JIN
;
Qing XIA
;
Dan DU
Author Information
1. 四川大学华西医院中西医结合中心,胰腺炎中心,四川 成都 610041
- Publication Type:Journal Article
- Keywords:
acute pancreatitis;
Wei-Qi-Ying-Xue;
transmission;
metabolism;
turbid toxin theory;
metabolic reprogramming;
metabolic homeostasis
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2025;41(3):300-305
- CountryChina
- Language:Chinese
-
Abstract:
There is a dynamic and progressive relationship in acute pancreatitis(AP),following the principle of Wei-Qi-Ying-Xue transmission in traditional Chinese medicine(TCM).The metabolic disorders prevalent in AP can be attributed to the"turbid tox-in"category in TCM,which runs throughout the disease as causative factors and pathologic products.The abnormal metabolism of sub-tle substances is the initiating factor of Wei-Qi-Ying-Xue transmission.Disorders of energy metabolism lay the pathologic basis of tur-bid evil and stagnant heat in the Qi stage of AP.Changes in the metabolic environment further exacerbate the inflammatory response re-sulting in the exuberance of pathogenic heat and the accumulation of blood stasis and toxins,promoting AP from the Qi division into the Ying-Xue stage.Therefore,we propose that"holding the Qi-fen juncture"and restoring metabolic homeostasis may be the keys to ear-ly truncation of AP disease progression.This paper explores the pathogenesis connotation of Wei-Qi-Ying-Xue transmission in AP from a metabolic perspective combined with the turbid toxin theory,which not only enriches the scientific connotation of Wei-Qi-Ying-Xue syndrome differentiation but also provides new ideas for the prevention and treatment of severe AP with TCM.
