Exploration of epidemiological characteristics of multidrug-resistant organisms among burn wound patients and prevention and control strategies based on worldwide database for nosocomial outbreaks
10.11816/cn.ni.2025-250922
- VernacularTitle:基于全球医院感染暴发数据库探讨烧伤患者多重耐药菌医院感染暴发流行特征及防控策略
- Author:
Jiao SHAN
1
;
Wei HUAI
;
Shanshan MENG
;
Meng JIN
;
Xiaoyuan BAO
;
Yulong CAO
;
Hong LI
;
Hui CHEN
Author Information
1. 首都医科大学附属北京积水潭医院医院感染管理处,北京 100035
- Publication Type:Journal Article
- Keywords:
Burn wound;
Hospital-acquired infection;
Multidrug-resistant organism;
Outbreak;
Epidemiology;
Prevention and control strategy;
Worldwide database for nosocomial outbreaks
- From:
Chinese Journal of Nosocomiology
2025;35(17):2592-2596
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the epidemiological characteristics of hospital-associated infections caused by multidrug-resistant organisms(MDROs)among the burn wound patients so as to provide bases for taking tar-geted control measures.METHODS A systematic search was conducted in the worldwide database for nosocomial outbreaks,PubMed and CNKI databases so as to summarize and analyze the data regarding to outbreaks of MDROs hospital-associated infections among burn wound patients.RESULTS A total of 61 incidents of MDROs hospital-associated infections outbreaks among the burn wound patients were included,involving 2 293 patients from 21 countries and regions,50(81.97％)of which were reported for the infection sites or colonization sites in-volving burn wound,12(19.67％)involving the respiratory tract,10(16.39％)involving the bloodstream infec-tions.Methicillin-resistant Staphylococcus aureus(28 incidents,45.90％)was dominant among the pathogens causing the infections,followed by multidrug-resistant Acinetobacter baumannii(17 incidents,27.87％)and multidrug-resistant Pseudomonas aureus(9 incidents,14.75％).52 incidents(82.25％)of outbreaks were reported the contact as the major transmission mode.The suspected sources of the outbreaks included the patients(37 incidents,28.46％),health care workers(30 incidents,23.08％),ward environments(28 incidents,21.54％),medical equipments(19 incidents,30.56％),drainage systems(6 incidents,4.62％).The major pre-vention and control measures included environmental cleaning and disinfection,screening of colonization in patients and health care workers,isolation of patients with infections and hand hygiene;8 incidents were taken the measure of closing the ward.CONCLUSIONS The outbreaks of MDROs infections in the burn wound patients are mostly associated with the high frequently contact environments,medical equipments and hand hygiene of health care workers.In view of the peculiarities of the burn wound patients,it is feasible to take the targeted measures based on the summarized prevention and control combinations for MDROs so as to prevent the outbreak of hospital-asso-ciated infections.
