Gut microbiota after kidney transplantation and its impact on patient prognosis
- VernacularTitle:肾移植术后肠道微生物群失调及其对患者预后的影响
- Author:
Pumeng FU
1
;
Yaping LIU
1
;
Mengru WANG
1
;
Qingqing YAO
1
;
Zhengyu REN
1
;
Hongxia LI
1
Author Information
- Publication Type:Journal Article
- Keywords: kidney transplantation; immunosuppressant; alloimmune rejection; gut microbiota; post-transplantation complication
- From: Journal of Xi'an Jiaotong University(Medical Sciences) 2025;46(6):900-909
- CountryChina
- Language:Chinese
- Abstract: In recent years,with the advancement of microbial detection technologies,an increasing number of studies have revealed significant differences in the gut microbiota composition of kidney transplant recipients before and after surgery.These changes in the gut microbiota may influence graft function and the occurrence of post-transplant complications through a variety of factors.This article will review the research progress in the relationship between gut microbiota and kidney transplantation.It focuses on the changes in gut microbiota after kidney transplantation.The role of gut microbiota in immune regulation,drug metabolism,graft function protection,and post-transplant complications is also studied.At the same time,these effects may be of great significance in improving the short-term and long-term prognosis of kidney transplant recipients,thus providing a novel idea for further improving kidney transplant prognosis.
