Progresses of structural and functional MRI in research of hippocampal changes in Alzheimer disease continuum
10.13929/j.issn.1003-3289.2025.09.030
- VernacularTitle:结构与功能MRI研究阿尔茨海默病连续体海马变化进展
- Author:
Qingqing SHANG
1
;
Bingyuan CHU
;
Ming YANG
;
Hanxi ZHANG
;
Xinlu LI
;
Ze FENG
;
Weiqing LI
;
Feng WANG
Author Information
1. 黑龙江中医药大学研究生院,黑龙江哈尔滨 150040
- Publication Type:Journal Article
- Keywords:
Alzheimer disease;
mild cognitive impairment;
hippocampus;
magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2025;41(9):1595-1599
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer disease(AD)is a neurological disease characterized by cognitive decline.AD continuum refers to the dynamic development progression from early pathological changes to obvious clinical symptoms,covering the continuous spectrum of subjective cognition decline(SCD)stage,mild cognitive impairment(MCI)stage and dementia stage.As one of the key brain regions involved in early stage,hippocampus(HP)in AD continuum is closely related to the progression of disease.MRI has been widely used in the study of HP in the AD continuum.The progresses in structural and functional MRI research of HP changes in AD continuum were reviewed in this article.