Transvaginal ultrasound parameters combined with clinical features for predicting success pregnancy or not of polycystic ovary syndrome patients with infertility after in vitro fertilization/intracytoplasmic sperm injection
10.13929/j.issn.1003-3289.2025.09.022
- VernacularTitle:腔内超声参数联合临床特征预测多囊卵巢综合征伴不孕患者接受体外受精或卵母细胞细胞质内单精子注射后能否成功妊娠
- Author:
Min LIU
1
;
Qian WANG
1
;
Liqiong LI
1
;
Ping LI
1
;
Xie HU
1
;
Dan WANG
1
Author Information
1. 乐山市人民医院超声医学科,四川乐山 614000
- Publication Type:Journal Article
- Keywords:
polycystic ovary syndrome;
ultrasonography;
treatment outcome;
forecasting
- From:
Chinese Journal of Medical Imaging Technology
2025;41(9):1558-1562
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of transvaginal ultrasound parameters combined with clinical features for predicting success pregnancy or not of polycystic ovary syndrome(PCOS)patients with infertility after in vitro fertilization/intracytoplasmic sperm injection(IVF/ICSI).Methods Totally 348 PCOS patients with infertility were retrospectively analyzed.Patients with presence of a gestational sac on ultrasound and did not experience miscarriage within 4 months after IVF/ICSI were classified as success pregnancy(pregnancy group,n=178),while the rest 170 patients were enrolled in non-pregnancy group.Univariable and multivariable logistic regression analyses were employed to assess clinical data,IVF/ICSI and transvaginal ultrasound parameters to identify the independent predictors of non-pregnancy in PCOS patients with infertility after IVF/ICSI,and a regression equation was constructed.The predictive efficacy,calibration and clinical value of this model were evaluated.Results Patients'age,duration of infertility,ovulation induction protocol(long protocol),duration of gonadotropin treatment,numbers of antral follicles and dominant follicles,total ovarian area,ovarian medullary area and endometrial thickness showed on transvaginal ultrasound before IVF/ICSI,as well as IVF with 2 pronuclei(IVF 2PN)and ICSI with 2 pronuclei(ICSI 2PN)or not were all independent predictors of success pregnancy or not in PCOS patients with infertility after IVF/ICSI(all P＜0.05).The area under the curve of the regression model was 0.771,and its predicted probabilities correlated with actual probabilities.Decision curve analysis indicated that the regression model had good clinical benefit.Conclusion Transvaginal ultrasound parameters combined with clinical features could effectively predict success pregnancy or not in PCOS patients with infertility after IVF/ICSI.
