MR intravoxel incoherent motion for analysis of placental microcirculation and microstructures in plateau area of late pregnancy induced hypertension and normal middle and late pregnancy women
10.13929/j.issn.1003-3289.2025.09.021
- VernacularTitle:MR体素内不相干运动对比分析高原地区妊娠高血压综合征孕晚期与正常孕中-晚期孕妇胎盘微循环及微结构
- Author:
Fei LIU
1
;
Zhanyue YAN
;
Zhengning GAN
;
Chenghuan LIU
;
Shenglan WANG
;
Linkui ZHANG
;
Gang LIU
Author Information
1. 青海红十字医院放射影像介入科,青海西宁 810000
- Publication Type:Journal Article
- Keywords:
hypertension,pregnancy-induced;
placenta;
microcirculation;
magnetic resonance imaging;
intravoxel incoherent motion;
plateau
- From:
Chinese Journal of Medical Imaging Technology
2025;41(9):1554-1557
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of MR intravoxel incoherent motion(IVIM)for analyzing placental microcirculation and microstructures in plateau area of late pregnancy induced hypertension(PIH)and normal middle and late pregnancy.Methods Totally 26 cases of PIH in late-trimester of pregnancy(group A)and 46 normal pregnant women(including 18 normal middle-trimester[group B]and 28 normal late-trimester[group C])in plateau area were retrospectively analyzed.The perfusion fraction(f),true diffusion coefficient(D)and pseudo-diffusion coefficient(D*)values of the entire placenta and the fetal side,maternal side and central region of placenta were obtained based on MR IVIM data,intra-and inter-group comparisons were conducted.Pearson correlation analysis was used to explore the relationships of placental IVIM parameters and maternal age,gestational age,estimated fetal weight(EFW)and neonatal birth weight.Results Except for f value of placental maternal side was higher than of fetal side in group C(P＜0.05),no significant difference was found in pairwise comparisons of IVIM parameters between different placental regions within each group(all P＞0.05).f value of the entire placenta and its fetal side,as well as D value of the entire placenta and its maternal side in group A were all higher than those in group C(all adjusted P＜0.05).The f and D* values of the entire placenta,f,D and D*values of its maternal side,as well as f and D* values of the fetal side in group C were all higher than those in group B(all adjusted P＜0.05).In group C,f value of placental maternal side was negatively correlated with both gestational age and EFW(r=-0.441,-0.579,both P＜0.01).Conclusion MR IVIM could be used to non-invasively assess placental microcirculation and microstructures in plateau area of late PIH and normal middle and late pregnancy women.
