Research progress of abnormal glucose and lipid metabolism and pathogenesis of sarcopenia
10.3969/j.issn.1006-6187.2025.11.013
- VernacularTitle:糖脂代谢异常与肌少症发病机制的研究进展
- Author:
Zhikai XU
1
;
Yu GAO
Author Information
1. 067000 承德医学院研究生学院
- Publication Type:Journal Article
- Keywords:
Sarcopenia;
Abnormal glucose and lipid metabolism;
Diabetes mellitus
- From:
Chinese Journal of Diabetes
2025;33(11):867-870
- CountryChina
- Language:Chinese
-
Abstract:
Sarcopenia refers to the gradual decrease in skeletal muscle mass and function with age,and is an important factor in disability and mortality in elderly population.The pathogenesis of sarcopenia may be related to insulin resistance,oxidative stress,inflammation,mitochondrial dysfunction,and impaired autophagy caused by abnormal glucose and lipid metabolism.Sarcopenia can reduce daily activity ability and prolong recovery time from diseases.This article reviews the research progress on the relationship between abnormal glucose and lipid metabolism and the pathogenesis of sarcopenia.
