The prognostic factors of post-ECT delirium and its subtypes
10.3760/cma.j.issn.1006-7884.2016.05.008
- VernacularTitle:改良电休克治疗后不同亚型谵妄的相关因素分析
- Author:
Xue YANG
1
;
Wei JIANG
;
Yanping REN
;
Changqing JIANG
;
Yilang TANG
Author Information
1. 哈尔滨第一专科医院精神科
- Publication Type:Journal Article
- Keywords:
Electroconvulsive therapy;
Delirium;
Risk factors
- From:
Chinese Journal of Psychiatry
2016;49(5):312-316
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the prognostic factors associated with each subtype of post-ECT delirium (PECTD).Methods Enrolled patients who received electroconvulsive therapy.Data collected included the demographic data,modified electroconvulsive therapy (MECT) treatment parameters and pre-MECT medications.Logistic regression analysis was used to examine the prognostic factors for hyperactive and hypoactive PECTD.Results 177 (52.8%) out of 335 patients enrolled in this study developed post-ECT delirium,118/177 (66.7%) were classified as hyperactive subtype and 59/177(33.3%)hypoactive subtype.Single factor analysis showed that,pre-ECT use of lithium (16/31,x2=5.239),benzodiazepines (30/75,Z=13.927),antipsychotic (107/132,x212.214) or antidepressants(16/37,x5=4.470)were significantly associated with hyperactive PECTD,but only pre-ECT lithium remained significant (OR=2.058,P=0.016) in logistic analysis.For active PECTD,logistic analysis showed that,comparing with younger age group,patients aged older than 60 years had a higher risk to develop hypoactive PECTD (OR=3.884,P=0.014),and those who received the first ECT had a higher risk to develop hypoactive PECTD (OR=4.891,P<0.01).Conclusions Pre-ECT lithium may be the prognostic factor for hyperactive PECTD,while the prognostic factors for hypoactive ECT include age greater than 60 years old and after first ECT treatment.