An outbreak of neonatal Pseudomonas aeruginosa infection caused by wa-ter contamination
10.12138/j.issn.1671-9638.20256959
- VernacularTitle:一起水污染引起的新生儿铜绿假单胞菌感染暴发调查
- Author:
Dan LIAO
1
;
Yanni WEI
;
Guiyi LIAO
;
Wenting LIANG
;
Zhangjie MA
;
Ying LIANG
Author Information
1. 广西医科大学基础医学院微生物学教研室,广西南宁 530021
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
sink;
handwashing sink;
healthcare-associated infection outbreak;
neo-natal intensive care unit;
contact isolation
- From:
Chinese Journal of Infection Control
2025;24(4):551-556
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the causes and intervention measure efficacy of an outbreak of neonatal Pseudo-monas aeruginosa(P.aeruginosa)infection in a medical institution.Methods The epidemiological investigation was conducted on 5 neonates who had P.aeruginosa infection in the neonatal intensive care unit(NICU)of this medical institution from May 26 to June 10,2024.Specimens were taken from potentially contaminated environ-ments to infer the cause of P.aeruginosa transmission in the NICU,infection control measures were also taken,and the efficacy of the control measures was continuously monitored.Results Among the 5 infected neonates,3 had lower respiratory tract infection and 2 had lower respiratory tract combined with bloodstream infection.Seven strains of P.aeruginosa were detected with a consistent antimicrobial resistance spectrum.Infected neonates were in the same ward and had spatial and temporal clustering.Through environmental hygiene monitoring,P.aerugi-nosa with consistent antimicrobial resistance spectrum of neonatal infection was isolated from the NICU handwashing sink and water-related environment(suction connection pipe,bedside isolation gowns).Infection was controlled af-ter improving sink disinfection methods and enhancing contact isolation measures,and no further P.aeruginosa was detected in the environment.Conclusion The outbreak of neonatal HAI in the NICU is inferred to be caused by contamination of ward handwashing sink by P.aeruginosa,then further contaminated the suction connection tube,thereby leading to the transmission of neonatal infection through suction procedures.Healthcare-associated infection surveillance and control professionals need to fully understand the characteristics of outbreak pathogens and take tar-geted measures to curb the transmission of neonatal infection.
