Effects of visuospatial function on balance function in patients with Alzheimer's disease
10.3760/cma.j.issn.1006-7884.2016.05.004
- VernacularTitle:阿尔茨海默病患者视空间功能与平衡功能的相关研究
- Author:
Mei JIN
1
;
Yuanyuan PAN
;
Wenjiao XIE
;
Hui OUYANG
;
Leping XU
Author Information
1. 解放军第八一医院门诊部
- Publication Type:Journal Article
- Keywords:
Alzheimer disease;
Cognition;
Visuospatial function;
Balance
- From:
Chinese Journal of Psychiatry
2016;49(5):286-291
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effects of visuospatial function on balance function in patients with Alzheimer's disease (AD).Methods A clinical balance function survey was conducted with Berg Balance Scales (BBS) on a total of 116 patients with mild-moderate AD.Judgment of line orientation test and visual form discrimination test,visual one objective continuous performance test,and Corsi block recall were used to assess the ability of visuospatial perception,visuospatial attention,and visuospatial working memory respectively in AD patients.Partial correlation was used for analysis of relationships between the results of visuospatial function test and BBS,while the logisitic analysis was used for the exploring of visuospatial function effects on balance function in AD patients.Results Subjects were defined as AD patients with impaired balance function (29 cases) with the scores of BBS lower than 46,or AD patients with normal balance function (87 cases) with the scores of BBS higher than or equal to 46.Compared to AD patients with normal balance function,AD patients with impaired balance function showed significant lower scores of judgment of line orientation test (12.8 ±2.6 vs.14.8 ± 3.0,t=3.218,P＜0.01),Corsi block recall (3.5±0.8 vs.4.1 ± 1.3,t=2.433,P＜0.05),and higher omission error rate of visual one objective continuous performance ((10.3±2.4)％ vs.(8.9± 1.4)％,t=2.986,P＜0.O1).Scores of judgment of line orientation test positively correlated with the scores of BBS (r=0.256,P＜0.01) and the scores of dynamic balance subscale of BBS (r=0.227,P＜0.01).Scores of omission error rate of visual one objective continuous performance negatively correlated with the scores of BBS (r=-0.310,P＜0.01),the scores of static balance subscale of BBS (r=-0.204,P＜0.01),and the scores of dynamic balance subscale of BBS (r=-0.305,P＜0.01).Logisitic analysis showed that the scores of judgment of line orientation test (OR=0.780,95％CI 0.653-0.931,P＜0.01) and the omission error rate of visual one objective continuous performance (OR=1.033,95％CI 1.004-1.062,P＜0.05)were associated with impaired balance function in AD patients.Conclusions The findings suggest that the worse visuospatial function,the worse balance function in AD patients.Visuospatial perception impairment and visuospatial attention function impairment may be independent risk factors of balance impairment in AD patients.
