A case report of Guillain-Barré syndrome associated with dengue fever
10.3969/j.issn.1002-0152.2025.03.006
- VernacularTitle:登革热相关性吉兰-巴雷综合征1例
- Author:
Wei LIN
1
;
Qiaozhen SU
;
Yufeng CHEN
;
Chunye ZHENG
Author Information
1. 广州中医药大学第二临床医学院(广州 510405)
- Publication Type:Journal Article
- Keywords:
Guillain-Barré syndrome;
Dengue fever;
Demyelinating diseases;
Case reports;
Clinical features
- From:
Chinese Journal of Nervous and Mental Diseases
2025;51(3):162-164
- CountryChina
- Language:Chinese
-
Abstract:
We report a 19-year-old male patient who developed numbness and weakness in the extremities,bilateral facial paralysis,difficulty swallowing,and slurred speech after the onset of dengue fever.Physical examination revealed decreased superficial and deep sensation below the knees,with absent tendon reflexes in the limbs.Cerebrospinal fluid analysis was normal,and ganglioside-related antibodies were negative.Electromyography showed multiple symmetric peripheral nerve demyelination in the limbs and facial nerves.The patient was diagnosed with Guillain-Barré syndrome.After receiving treatment with immunoglobulin and corticosteroids,his symptoms improved,and he made a good recovery during follow-up.Dengue fever has been rarely reported as a preceding infection of Guillain-Barré syndrome in China.This case report,along with a review of relevant literature,aims to enhance the understanding of the diagnosis and management of this condition.It emphasizes the importance of early diagnosis and treatment by clinicians to avoid misdiagnosis and missed diagnosis of dengue-related Guillain-Barré syndrome.
