Research progress on stem cell-loaded hydrogels in promoting wound healing
10.16753/j.cnki.1008-2344.2025.06.015
- VernacularTitle:干细胞负载水凝胶在促进伤口愈合中的研究进展
- Author:
Bingchen CHU
1
;
Rui HUANG
;
Haiying HUANG
Author Information
1. 安徽理工大学第一附属医院,安徽 淮南 232000
- Publication Type:Journal Article
- Keywords:
wound healing;
hydrogel;
stem cells;
cell therapy
- From:
Journal of Shenyang Medical College
2025;27(6):649-654
- CountryChina
- Language:Chinese
-
Abstract:
Wound healing is a significant medical challenge,particularly in the treatment of chronic wounds.Traditional therapeutic methods often fall short in addressing the complex demands of chronic wounds,such as diabetic foot ulcers and deep burns.Recently,the combination of hydrogels and stem cell technology has offered new hope for wound treatment.Hydrogels,with their excellent moisturizing properties,breathability,and biocompatibility,have become ideal materials for wound coverage.Stem cells,renowned for their regenerative and tissue repair capabilities,are highly valued in this context.Hydrogels provide a three-dimensional scaffold that mimics the wound site's natural environment,promoting the adhesion,growth,and differentiation of stem cells.They can also be engineered as delivery systems to release growth factors or drugs in a controlled manner,directly targeting the treatment area and accelerating the healing process.Meanwhile,stem cells enhance the repair functions of surrounding tissues by secreting growth factors and cytokines,improving local blood circulation,and reducing inflammation.This article reviews the development and application of hydrogels combined with stem cells in promoting wound healing,in order to provide new ideas and strategies for the clinical treatment of chronic wounds.
