Risk factor analysis and clinical correlation of ligamentum flavum hypertrophy in degenerative lumbar spinal stenosis
10.3969/j.issn.1002-1671.2025.11.018
- VernacularTitle:退行性腰椎椎管狭窄症中黄韧带肥厚的危险因素分析及临床相关性研究
- Author:
Hang SHI
1
;
Kangjia YANG
1
;
Xiaopeng SUN
1
;
Xingyu ZHU
1
;
Lixuan SUN
1
;
Hua DING
1
Author Information
1. 江苏大学附属人民医院骨科,江苏 镇江 212002
- Publication Type:Journal Article
- Keywords:
degenerative lumbar spinal stenosis;
ligamentum flavum thickness;
lumbar lordosis;
paraspinal muscle fat infiltration;
epidural fat
- From:
Journal of Practical Radiology
2025;41(11):1842-1846
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors for ligamentum flavum hypertrophy(LFH)and its correlation with clinical symptoms in patients with degenerative lumbar spinal stenosis(DLSS).Methods The clinical and imaging data of 79 patients with DLSS were collected.Patients were divided into four groups based on LFH severity.Quantitative parameters,including lumbar lordosis(LL),sacral slope(SS),facet tropism,facet joint effusion,intervertebral height index,dural sac cross-sectional area(CSA),epidural fat area,and fat infiltration rate(FIR)of the paraspinal muscle were measured on imaging.One-way analysis of variance was used to compare the differences in these parameters among groups.Multiple linear regression analysis was performed to identify the risk fac-tors for LFH,and the correlation between LFH severity and clinical manifestations was analyzed.Results The results of one-way analy-sis of variance showed that there were statistically significant differences among the four groups of patients in terms of sex,body mass index(BMI),LL,epidural fat area and FIR of the multifidus(MF).Multiple linear regression analysis identified that BMI,LL,and epidural fat area as independent risk factors for LFH.Correlation analysis indicated a weak positive association between LFH and dis-ease duration(r=-0.231,P=0.041).Conclusion In DLSS patients,LFH is weakly correlated with disease duration,while BMI,LL,and epidural fat area are risk factors for LFH.
