Research Progress in the Mechanism of Shaoyao Decoction in Regulating Cytokines for the Treatment of Ulcerative Colitis
10.19879/j.cnki.1005-5304.202412531
- VernacularTitle:芍药汤调控细胞因子治疗溃疡性结肠炎作用机制研究进展
- Author:
Cuicui LIU
1
;
Peng'an YAN
;
Xi CUI
;
Qinqin LIU
;
Hanghang LI
;
Rui ZHAI
;
Shuxun SHI
Author Information
1. 甘肃中医药大学,甘肃 兰州 730000
- Publication Type:Journal Article
- Keywords:
ulcerative colitis;
Shaoyao Decoction;
cytokines;
immunomodulatory;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2025;32(10):179-184
- CountryChina
- Language:Chinese
-
Abstract:
Ulcerative colitis(UC)is a recurrent,chronic,nonspecific inflammatory bowel disease.Shaoyao Decoction has shown good efficacy in the treatment of UC,which mainly regulates the balance of cytokines to achieve the purpose of treating UC.This article reviewed the research progress in the mechanism of Shaoyao Decoction in the treatment of UC from two aspects of pro-inflammatory cytokines and anti-inflammatory cytokines.Research has shown that Shaoyao Decoction can regulate the body's immune response,alleviate intestinal inflammation,protect the intestinal mucosal barrier,restore normal structure and function of the colon mucosa through pro-inflammatory cytokines such as tumor necrosis factor-α,interferon-γ,interleukin(IL)-1β,IL-6,IL-8,IL-17,and anti-inflammatory cytokines such as transforming growth factor-β,IL-4,IL-10,IL-13,which can provide reference for UC related mechanism research and clinical treatment.
