Atmospheric oxygen coupled with hyperbaric oxygen in the treatment of neurologic impairment with hemorheology in senile patients following hypertensive cerebral infarction
10.3760/cma.j.issn.1009-6906.2016.05.012
- VernacularTitle:常压氧联合高压氧治疗老年高血压性脑梗死患者神经功能缺损及血液流变学的改变
- Author:
Genqiang FANG
1
;
Genfa WAN
1
Author Information
1. 上海交通大学医学院附属新华医院老年医学科,上海,200092
- Publication Type:Journal Article
- Keywords:
Senile;
Hypertension;
Cerebral infarction;
Atmospheric oxygen;
Hyperbaric oxygen
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2016;23(5):378-381
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy of atmospheric oxygen coupled with hyperbaric oxygen (HBO) in the treatment of neurologic impairment with hemorheology in senile patients following hypertensive cerebral infarction.Methods Ninety-three senile patients with hypertensive cerebral infarction treated in our hospital were recruited as research subjects,and were divided into the observation group (48 cases) and the control group (45 cases) in accordance with different treatment methods.The observation group was treated with atmospheric oxygen couple with hyperbaric oxygen therapy,while the control group was only given HBO therapy.Then,differences in the clinical efficacy and changes in hemorheology were closely observed and compared between the 2 groups.Results Total efficacy of the observation group (97.9％) was significantly higher than that of the control group (82.2％),and statistical significance could be noted,when comparisons were made between them (P ＜ 0.05).There was no statistical significance in neurological deficit scores and Barthel scores for the 2 groups before treatment (P ＞ 0.05).However,those scores of the observation group after treatment [(7.4 ±4.1),(56.3 ± 15.2)] were significantly superior to those of the control group [(11.2 ± 5.4),(43.3 ± 10.7)],and statistical significance could be seen when comparisons were made between them(P ＜ 0.05).Following treatment,the parameters of blood pressure and changes in hemorheology of the observation group were significantly superior to those of the control group,with statistical significance (P ＜ 0.05).Conclusions In the treatment of neurologic impairment with hemorheology of senile patients,atmospheric oxygen coupled with HBO could achieve better clinical efficacy,and this treatment regimen was of positive significance for the recovery of neural function and improvement of life quality of the patients.
