Clinical evaluation of comprehensive hyperbaric oxygen therapy in the treatment of flat type sudden hearing loss
10.3760/cma.j.issn.1009-6906.2016.05.014
- VernacularTitle:高压氧综合治疗平坦型突发性聋临床疗效分析
- Author:
Qinghua LIU
1
;
Wenjia ZHAO
1
;
Pengjun XU
1
;
Qinggang MENG
1
Author Information
1. 上海交通大学医学院附属新华医院急诊科, 上海,200092
- Publication Type:Journal Article
- Keywords:
Hyperbaric oxygen;
Flat type;
Sudden deafness;
Hearing loss
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2016;23(5):386-389
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy of hyperbaric oxygen (HBO) in the treatment of flat type sudden hearing loss (SHL).Methods A retrospective analysis was made on 71 cases of flat type SHL treated with HBO.The patients were treated with HBO once a day,10 days a treatment course.Pure-tone averages (PTAs) at 4 frequencies (500,1 000,2 000,4 000 Hz) were compared before and after HBO therapy,and therapeutic efficacy was analyzed.Results Forty-four patients (the invalid group) began HBO therapy,when conventional treatment was invalid.PTAs before and after HBO therapy were respectively (59.50 ± 10.58) dB HL and (39.18 ± 18.95) dB HL,and statistical significance could be noted,when comparisons were made between them (P ＜ 0.01).Twenty-seven patients (the initial group) received HBO therapy at the initial treatment stage.PTAs for the patients of this group before and after HBO therapy were respectively (60.81 ± 10.40) dB HL and (31.89 ± 16.24) dB HL,and there was statistical significance,when comparisons were made between them (P ＜ 0.01).Total efficacy rates for the 2 groups after treatment were respectively 61.36％ and 81.48％,and statistical significance could be seen,when comparisons were made between them(t =8.566,P ＜ 0.01).The treatment time from the onset to HBO therapy for the patients of the 2 groups was (16.32 ± 3.65) days and (9.07 ± 6.85) days respectively,and statistical significance could be noticed,when comparisons were made between the 2 groups (P ＜0.01).The treatment time from the onset to HBO therapy for the invalid group was ＞ 14 days,accounting for 53.33％ of the patients treated(30/44),while the treatment time from the onset to HBO therapy for the initial group was ≤ 14 days,accounting for 90.0％ (20/27),and statistical significance could also be noted,when comparisons were made between the 2 groups(P ＜ 0.01).When correlative analyses were made between HBO initiation time and effective rate,it could be seen that HBO initiation time was positively correlated with treatment efficacy (r =0.434,P ＜ 0.01).Conclusions HBO therapy could be used as one of the methods in the comprehensive treatment of flat type SHL,and the earlier HBO treatment was implemented,the better the results.
