Hemorheological changes in the patients with cervical spondylopathy of vertebral artery following hyperbaric oxygen therapy
10.3760/cma.j.issn.1009-6906.2016.02.007
- VernacularTitle:高压氧治疗椎动脉型颈椎病血液流变学的变化
- Author:
Yun ZHANG
1
;
Yu ZENG
;
Ying JIANG
;
Min LIAO
;
Yong LUO
;
Linhui ZHANG
Author Information
1. 四川省人民医院中医骨科, 成都,610072
- Publication Type:Journal Article
- Keywords:
Hyperbaric oxygen;
Vertebral artery cervical spondylopathy;
Hemorheology
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2016;23(2):107-111
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of HBO on hemorheology of the patients with cervical spondylopathy of vertebral artery (CSA).Methods One hundred and seventy-five CSA patients who received medical care in our hospital from May 2011 to Oct 2014 were selected for the study.With the knowledge and consent of the patients and following the signing of the letter of agreement,the patients were randomly divided into 3 groups:the HBO group (n =60),the acupuncture group (n =58) and the massage group (n =57).The 3 groups were all given treatment once a day,with 10 days a treatment course.At day 0,10 days after the start of treatment,and 1 month after completion of treatment (or at day 40),all the patients were evaluated by using the Cervical Vertigo Symptom and Function Assessment Scale (CVSFAS).At the same time,hemorheologic data were detected in all the patients before treatment,at day 5 and day 10 after the start of treatment and 1 month after completion of treatment (or at day 40).Pair T test was performed for intra-group comparison,and variance analysis of vertigo scores at different time points after the start of treatment and comparison of various hemorheologic data were performed by using repeated measurement data.Results Statistical significance could be seen in the vertigo scores before and after treatment,when comparisons were made between the 3 groups (P ＜ 0.05).However,no statistical significance could be noticed in the vertigo scores at different time points after treatment,when comparisons were made between the 3 groups (P ＞ 0.05),indicating that the 3 treatment schemes could all effectively improve the dizziness and headache of the patients and no obvious differences could be noted in the therapeutic.Statistical significance could also be seen in various hemorheologic data at different time points after treatment,as compared with those before treatment (P ＞ 0.05),indicating that the 3 treatment could all affect hemorheology.One month after completion of the treatment,minimal changes could be found in various hemorheologic data in the HBO group.Statistical significance could also be seen in various hemorheologic data at day 10,as compared with those at day 40 (P ＞0.05).Forty days after treatment,no statistical significance could be noted in various hemorheologic data,when comparisons were made between the 3 groups (P ＞ 0.05),indicating that HBO could affect hemorheology for a considerable length of time.Conclusions The application of HBO in the treatment of CSA could improve dizziness and headache,reduce high shear blood viscosity,as well as low shear blood viscosity,decrease such data as RBC hematocrit,plasma viscosity and fibrinogen,consequently decreasing blood viscosity and affecting hemorheology.
