Research status of arsenic (organoarsenic) compounds applied in medicine
10.3760/cma.j.cn231583-20231024-00092
- VernacularTitle:砷（胂）化合物在医学史上应用的研究现状
- Author:
Hui LU
1
;
Guangze YAO
;
Yujie WEI
;
Hui WANG
;
Xinyang ZHAO
;
Senlin ZHU
;
Yiling LIU
;
Qianlei YANG
;
Yan AN
Author Information
1. 苏州大学苏州医学院公共卫生学院卫生毒理学系，苏州215123
- Publication Type:Journal Article
- Keywords:
Arsenic;
Arsenic trioxide;
Medical use;
Anticancer;
Antiviral;
Antibiotic
- From:
Chinese Journal of Endemiology
2025;44(3):253-258
- CountryChina
- Language:Chinese
-
Abstract:
Arsenic (organoarsenic) compound is one of the oldest drugs used by humans to treat various diseases. From its initial application in treating various skin diseases to the 1970s when arsenic trioxide (ATO) was proven to be able to significantly relieve acute promyelocytic leukemia (APL), arsenic (organoarsenic) compounds gradually occupied an important position in the history of medical development. This article reviews the pharmaceutical research progress of inorganic arsenic compounds and organic arsine compounds, covering anticancer, antiparasitic, antiviral and antibiotic aspects. It further explores the potential for developing new arsenic (organoarsenic) drugs with higher efficacy and lower toxicity, aiming to provide new research directions and ideas for the application of arsenic (organoarsenic) compounds in disease treatment.
