Analysis of influencing factors of adult dental fluorosis in drinking water-borne endemic fluorosis areas of Inner Mongolia Autonomous Region in 2024
10.3760/cma.j.cn231583-20240604-00164
- VernacularTitle:2024年内蒙古自治区饮水型地方性氟中毒病区成人氟斑牙的影响因素分析
- Author:
Fan ZHAO
1
;
Zhong YANG
;
Kaifeng XU
;
Fenxia LI
;
Shifang ZHANG
;
Xinye LI
;
Cong LIU
;
Mengxin LI
;
Yuchen GUO
;
Tianrui ZHUANG
;
Ke LI
;
Zhixian YANG
;
Danyu DENG
;
Zhongbing ZHANG
;
Zhiwei GUO
Author Information
1. 内蒙古医科大学公共卫生学院，呼和浩特010110
- Publication Type:Journal Article
- Keywords:
Adult;
Dental fluorosis;
Drinking water-borne endemic fluorosis;
Influencing factors
- From:
Chinese Journal of Endemiology
2025;44(3):232-236
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the influencing factors of adult dental fluorosis in drinking water-borne endemic fluorosis areas of Inner Mongolia Autonomous Region.Methods:A case-control study was conducted in January 2024 to select adult fluorosis patients (case group) and healthy individuals (control group) from the drinking water-borne endemic fluorosis areas in Helinger County, Hohhot City, Inner Mongolia Autonomous Region as the survey subjects. Urine samples were collected to determine urinary fluoride concentration. A questionnaire survey was conducted. SPSS 25.0 software was used for χ 2 test and multivariate logistic regression analysis. Restricted cubic spline (RCS) was used to analyze the association between urinary fluoride concentration and the risk of dental fluorosis in adults. Results:A total of 161 individuals were included in the survey, including 100 in the case group and 61 in the control group. The results of univariate analysis showed that there were statistically significant differences in the distribution of gender, smoking, and urinary fluoride concentration between the case group and the control group (χ 2 = 7.54, 5.02, 9.69, P < 0.05). The results of multivariate logistic regression analysis indicated that gender ( OR = 0.36, 95% CI: 0.18 - 0.73, P = 0.005) and urinary fluoride concentration ( OR = 3.08, 95% CI: 1.46 - 6.67, P = 0.003) were the influencing factors of adult fluorosis. RCS analysis showed a significant linear dose-response relationship between the risk of dental fluorosis and urinary fluoride concentration ( Poverall trend = 0.001, Pnonlinear = 0.071). When the urinary fluoride concentration was greater than 1.57 mg/L, the risk of dental fluorosis increased with the increase of urinary fluoride concentration. Conclusion:Gender and urinary fluoride concentration are the risk factors of dental fluorosis in adults in drinking water-borne endemic fluorosis areas of Inner Mongolia Autonomous Region.
