Advances in stem cell therapy for islet function remodeling
10.3760/cma.j.cn311282-20241218-00600
- VernacularTitle:干细胞治疗重塑胰岛功能的研究进展
- Author:
Sijie ZHANG
1
;
Fangzhou LU
1
;
Qi FU
1
;
Tao YANG
1
Author Information
1. 南京医科大学第一附属医院内分泌科，南京 210029
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Islet function;
Stem cell therapy;
Islet remodeling
- From:
Chinese Journal of Endocrinology and Metabolism
2025;41(10):878-882
- CountryChina
- Language:Chinese
-
Abstract:
Diabetes mellitus, primarily caused by insulin deficiency or insulin resistance, is a metabolic disorder characterized by hyperglycemia. It has become a global public health priority. In addressing the core issue of pancreatic dysfunction, the limitations of traditional treatments have become increasingly apparent, leading to a growing interest in novel strategies for islet function remodeling. With advancements in stem cell technology, stem cell therapy is emerging as a promising approach for islet function restoration. This review summarizes recent progress in stem cell therapy for islet function remodeling, with a particular focus on the application of stem cell technology to in vitro islet reconstruction, offering new insights for the development of efficient and safe therapeutic strategies for diabetes.
