Pathogenesis,syndrome differentiation,and treatment of chronic prostatitis based on the"host-guest interaction-collateral disease"theory
10.3969/j.issn.1006-2157.2025.07.013
- VernacularTitle:基于"主客交-络病"理论探讨慢性前列腺炎的病机及辨治
- Author:
Yi WEI
1
;
Zhiming HONG
;
Junfeng QIU
;
Zilong CHEN
;
Shengjie WANG
;
Wenshuo CHEN
;
Lianqin ZHANG
;
Chunxiu CHEN
Author Information
1. 广州中医药大学第四临床医学院 深圳 518033
- Publication Type:Journal Article
- Keywords:
host-guest interaction;
collateral disease;
chronic prostatitis;
function through free flow;
combination of unblocking and tonifying
- From:
Journal of Beijing University of Traditional Chinese Medicine
2025;48(7):979-984
- CountryChina
- Language:Chinese
-
Abstract:
Chronic prostatitis,a common condition in andrology,is clinically characterized by a prolonged course,resistance to treatment,and frequent recurrence.In traditional Chinese medicine,it is classified under the categories of"turbid sperm,""overstrain strangury,"and"vaginal pain."Based on the"host-guest interaction-collateral disease"theory,we believe that healthy qi deficiency,latent pathogenic factors,and collateral obstruction are the primary pathological factors of this disease,which run through the entire process of chronic prostatitis occurrence and development.Accordingly,we propose that obstruction of collaterals and apathesia of the semen chamber are the core pathogenesis.The disease progression can be divided into three pathological stages:"deficiency,depression,and blood stasis."Spleen and kidney deficiency and malnutrition of collaterals form the pathological foundation.In the deficiency stage,treatment strategies involve reinforcing qi and nourishing the collaterals,using Fuzheng Yangrong Decoction.During disease progression,dampness and heat invasion,as well as collateral stagnation qi,are key contributors to disease progression.Thus,treatment focuses on clearing heat and dampness,promoting qi flow,and smoothing the collaterals,achieved with a modified Qiantongding Decoction.In the final stage,blood stasis and collateral obstruction dominate,warranting therapeutic strategies aimed at tonifying and removing blood stasis,addressing both the body and the collaterals simultaneously using the modified Guiling Huayu Decoction.Overall,the clinical treatment generally focuses on the concept of function through free flow,combination of unblocking and tonifying.This study provides a novel perspective and reference for clinical differentiation and treatment of chronic prostatitis.
