Clinical management of unlocalized ACTH-dependent Cushing′s syndrome
- VernacularTitle:无法明确定位的ACTH依赖性库欣综合征临诊应对
- Author:
Yifan DU
1
;
Junyan YU
1
;
Jiabin LIN
1
;
Chengzhi WANG
1
;
Chulin HUANG
1
;
Tingting ZENG
1
;
Kan SUN
1
Author Information
- Publication Type:Journal Article
- Keywords: Cushing′s syndrome; Cushing′s disease; Ectopic ACTH syndrome; Hypokalemia
- From: Chinese Journal of Endocrinology and Metabolism 2025;41(7):578-583
- CountryChina
- Language:Chinese
- Abstract: Cushing′s syndrome refers to a group of disorders caused by excessive secretion of adrenal glucocorticoid due to various underlying etiologies. Among these, ACTH-dependent Cushing′s syndrome, in which the source of ACTH-secretion remains unclear for extended periods, poses significant challenges in clinical management. This article presents a patient with ACTH-dependent Cushing′s syndrome where the ACTH-secreting source could not be definitively localized from our hospital. Additionally, the article reviews recent advancements in the diagnosis and treatment of such cases, both domestically and internationally, with the aim of enhancing clinicians′ understanding and improving the management of this condition.
