Telomere length and metabolic diseases
10.3760/cma.j.cn311282-20240713-00312
- VernacularTitle:端粒长度与代谢性疾病的研究进展
- Author:
Junru FAN
1
;
Yufang BI
1
Author Information
1. 上海交通大学医学院附属瑞金医院内分泌代谢病科，上海市内分泌代谢病研究所，国家代谢性疾病临床医学研究中心（上海），上海 200025
- Publication Type:Journal Article
- Keywords:
Telomeres;
Telomere length;
Metabolic diseases
- From:
Chinese Journal of Endocrinology and Metabolism
2025;41(3):250-254
- CountryChina
- Language:Chinese
-
Abstract:
Telomeres are protective structures at the ends of chromosomes that help maintain chromosomal stability, with their DNA shortening after each cell division. As a result, telomere length is widely regarded as a biological marker of aging. Telomere length is closely associated with various metabolic diseases, and research has shown a correlation between leukocyte telomere length and the prevalence, progression, and mortality rate of these conditions. This suggests that telomeres may play a role in the onset and development of metabolic diseases, and telomere length could serve as a potential biomarker for tracking disease progression. This article reviews the current research on telomere length in metabolic diseases such as diabetes, obesity, and metabolic syndrome.
