High-normal blood pressure in different trimesters and its impact on incidence of hypertensive disorders and adverse maternal-fetal outcomes:a retrospective study
10.3969/j.issn.1672-8467.2025.04.020
- VernacularTitle:不同妊娠期正常高值血压与妊娠期高血压发病及不良母胎结局关系的回顾性研究
- Author:
Lu-yi MAO
1
;
Jiu-rong LI
1
;
Qing-ying ZHANG
1
Author Information
1. 复旦大学附属妇产科医院产科 上海 200011
- Publication Type:Journal Article
- Keywords:
hypertensive disorders of pregnancy(HDP);
high-normal blood pressure;
adverse maternal-fetal outcomes;
preterm birth;
small for gestational age(SGA)
- From:
Fudan University Journal of Medical Sciences
2025;52(4):605-610
- CountryChina
- Language:Chinese
-
Abstract:
The impact of hypertensive disorders of pregnancy(HDP)on maternal and fetal outcomes is well-established.However,the relationship between high-normal blood pressure(BP)and HDP,as well as its association with adverse maternal-fetal outcomes,remains unclear.This retrospective study analyzed singleton pregnancies delivered at Obstetrics and Gynecology Hospital,Fudan University from Jan 2021 to Dec 2021.Participants were categorized into a normal BP group(BP<130/80 mmHg before delivery admission)and two high-normal BP groups(BP:130-139/80-89 mmHg)with subgroup analysis based on gestational week of BP elevation before and after 20 weeks.Maternal characteristics,HDP incidence and adverse outcomes were compared across groups.The results demonstrated that compared with the normal BP group,both high-normal BP groups showed significantly increased HDP incidence,with more pronounced risk in the high-normal BP(after 20 weeks)group.The high-normal BP(before 20 weeks)group was associated with elevated risks of iatrogenic preterm birth and small for gestational age(SGA).This study provides a theoretical basis for implementing stricter BP monitoring strategies to reduce adverse maternal and neonatal outcomes.
