Changes in the prevalence of human parainfluenza virus in hospitalized children with respiratory tract infection in Hebei region
10.3760/cma.j.cn112309-20231019-00105
- VernacularTitle:河北地区住院儿童副流感病毒感染变化
- Author:
Yu ZHAI
1
;
Zheng FANG
;
Suxia DUAN
;
Teng LIU
;
Mengchuan ZHAO
;
Yinghui GUO
Author Information
1. 河北省儿童医院检验科，石家庄 050031
- Publication Type:Journal Article
- Keywords:
Respiratory tract infection;
Human parainfluenza virus;
Children;
Epidemiology
- From:
Chinese Journal of Microbiology and Immunology
2024;44(12):1005-1010
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the epidemiological characteristics of human parainfluenza virus (HPIV) in hospitalized children with acute respiratory tract infection in Hebei region, providing reference for the diagnosis and prevention of children with respiratory tract infection.Methods:A retrospective analysis was performed on 20 577 children hospitalized with acute respiratory tract infection in Hebei Children′s Hospital from January 2022 to September 2023. Multiple PCR and capillary electrophoresis were used to detect HPIV and 12 other common respiratory viruses and atypical pathogens. The data from January to September 2022 were taken as the normalized epidemic prevention and control period, and the data from January to September 2023 were taken as the normalized epidemic control period. The epidemiological characteristics of HPIV were analyzed.Results:The overall HPIV-positive rate was 13.65% (2 808/20 577). There was no statistical difference in the total detection rate of HPIV [14.24%(1 236/8 679) and 14.35%(1 447/10 087)] at the same time before and after the novel coronavirus normalization prevention and control was lifted(χ 2= 0.041, P=0.839), while the detection rate of single infection [8.96%(778/8 679) and 7.58%(765/10 087)] decreased, while mixed infection [5.28%(458/8 679) and 6.76%(682/10 087)] increased, with statistically significant differences(χ 2= 11.776 and 18.008, P<0.01). The HPIV positive rate in the <1 year [18.53%(378/2 040) and 17.08%(369/2 161)] decreased after the release of normalized prevention and control, and the difference was statistically significant(χ 2= 5.932, P<0.05). The HPIV positive rate [13.03%(382/2 932) and 14.82%(529/3 570)] in the 3-5 years increased after the normalized prevention and control was lifted, and the difference was statistically significant(χ 2= 7.177, P<0.05). The rate of mixed infection of HPIV with other respiratory pathogens was 43.13% (1 211/2 808), among which double infection was 34.40% (966/2 808), triple infection was 7.55% (212/2 808), and quadruple infection was 1.18% (33/2 808). Mixed detection of HPIV and HRV (38.65%, 468/1 211) was the most common. Conclusions:HPIV is one of the respiratory pathogens in children in Hebei region and more prevalent in spring and summer. The susceptible population of HPIV is mainly children under the age of 3 years old. After the normal prevention and control of novel coronavirus was lifted, the detection rate of HPIV combined with other pathogens increased.
