Efficacy of hyperbaric oxygen combined with 0.025％ ipratropium bromide inhalation in the treatment of stable chronic obstructive pulmonary disease patients
10.3760/cma.j.issn.1009-6906.2016.01.009
- VernacularTitle:高压氧联合0.025％异丙托溴铵雾化吸入对稳定期慢性阻塞性肺疾病患者的疗效观察
- Author:
Yingmin ZHANG
1
;
Yimin MAO
1
;
Yuxia SUN
1
Author Information
1. 河南科技大学第一附属医院呼吸科, 河南省洛阳,471000
- Publication Type:Journal Article
- Keywords:
Hyperbaric oxygen;
Ipratropium bromide;
Chronic obstructive pulmonary disease;
Atomization
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2016;23(1):36-38
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy of hyperbaric oxygen (HBO) combined with 0.025％ ipratropium bromide inhalation in the treatment of the patients with stable chronic obstructive pulmonary disease (COPD).Methods Eighty patients with stable COPD treated in our hospital from January 2013 to September 2014 were selected for the study by random sampling method.With the knowledge of the patients and approval of the ethics committee,the patients were randomly divided into the study group and the control group,each consisting of 40 patients.The control group was given pure 0.025％ ipratropium bromide inhalation therapy,while the study group received HBO combined with 0.025％ ipratropium bromide inhalation.Results The levels of forced vital capacity (FVC),forced expiratory volume in one second (FEVI),forced expiratory flow between 25 and 75％ of forced vital capacity (FEF25％-75％),peak expiratory flow (PEF) levels and partial pressure of oxygen in artery levels (PaO2) of the study group were significantly higher than those of the control group (P ＜ 0.05).There was no significant difference in the incidence of side effects after treatment,when comparisons were made between the 2 groups [5.0％ (2/40) 、0] (P ＞ 0.05).Conclusions HBO combined with 0.025％ ipratropium bromide inhalation was effective in the treatment of patients with stable COPD,with this reason,it was worth further clinical extension.
