Morbidity of hyperuricemia and kidney injury among shipboard personnel during prolonged deployment at sea and analysis of risk factors
10.3760/cma.j.issn.1009-6906.2015.03.008
- VernacularTitle:某部舰艇长航人员高尿酸血症和肾损伤患病率及相关因素分析
- Author:
Zhiyong ZHANG
1
;
Mingxu LI
1
;
Tao SUN
1
;
Jing XIA
1
;
Xiaobin YANG
1
Author Information
1. 海军总医院, 北京,100048
- Publication Type:Journal Article
- Keywords:
Hyperuricemia;
Kidney injury;
Risk factors;
Analysis of risk factors
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2015;(3):196-199
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the morbidity of hyperuricemia ( HUA ) and kidney injury ( KI ) among shipboard personnel of a certain naval unit during prolonged deployment at sea and analysis of related risk factors, so as to provide evidence for the development of related prevention and treatment measures . Methods Medical detections were made on 356 male shipboard personnel , who received physical check-ups from June to August , 2013 in the hospital .The physical check-up items included: serum uric acid ( SUA ) , blood lipids (TC, TG, HDL and LDL), blood sugar(FPG, FINS), hepatic function(ALT, GGT, ALP, TP, ALB, TBILI and DBILI), renal function(Scr, BUN) and serum ferritin (SF).Data were analyzed by bivariate analysis and multivariate logistic regression models , to explore the correlation between HUA , KI and nutritional status and the above data .Results Results indicated that there were respectively 221 cases of HUA and KI , with a morbidity rate of 62% ( 221/356 ) , and there were 166 cases that had both HUA and KI .The HUA patients with SUA levels between 417-467μmol/L had the highest morbidity .Bivariate analysis revealed that SUA was closely associated with the levels of TG , HDL, TP, TBILI, DBILI, BUN, eGFR and BG. Multivariate logistic regression further indicated SUA was uniquely related to TP and eGFR (P <0.05). Conclusions The HUA in the shipboard naval personnel seemed to have its epidemiological features , with the morbidity being much higher than that of the normal people , which might be associated with kidney injury . Measures should be taken for early prevention and timely treatment of the disorder clinically .
