Reconstruction of huge defect after radical surgery for locally advanced breast cancer with combination of pedicled and free perforator flaps: a case report
10.3760/cma.j.cn441206-20250207-00027
- VernacularTitle:带蒂结合游离皮瓣修复局部晚期乳腺癌根治术后巨大缺损创面1例
- Author:
Yong PAN
1
;
Shaoli LIU
1
;
Zhangcan LI
1
;
Buguo CHEN
1
;
Dawei ZHENG
1
;
Hui ZHU
1
;
Rongjian SHI
1
Author Information
1. 徐州仁慈医院显微修复重建外科,徐州 221004
- Publication Type:Journal Article
- Keywords:
Transverse rectus abdominis myocutaneous flap;
Deep inferior epigastric artery perforator flap;
Anterolateral thigh perforator flap;
Advanced breast canc
- From:
Chinese Journal of Microsurgery
2025;48(4):472-475
- CountryChina
- Language:Chinese
-
Abstract:
In October 2023, a patient with locally advanced breast cancer was treated in the Department of Reconstructive Microsurgery, Xuzhou Renci Hospital. Radical mastectomy for breast cancer was performed, and the huge soft tissue defect (40.0 cm×22.0 cm) was reconstructed by a pedicled transverse rectus abdominis myocutaneous flap (TRAMF) combined with a free deep inferior epigastric artery perforator flap (DIEPF) and a free anterolateral thigh perforator flap (ALTPF). The size of the lower abdominal flap was 28.0 cm×11.0 cm, and the size of ALTPF was 30.0 cm×11.0 cm. All flaps survived well with soft texture. Scores of Karnofsky Performance Status (KPS) and Visual Analogue Scale (VAS) were significantly improved at 1 month after the surgery. The patient refused chemotherapy, radiotherapy and other comprehensive treatments at the time. A local cancer recurrence in chest wall was found at 9 months after surgery, the patient was currently under chemotherapy and other comprehensive therapies.