Comparison of bowel preparation for colonoscopy between oral sulfate solution and polyethylene glycol electrolytes powder:a cohort study based propensity score matching
- VernacularTitle:硫酸镁钠钾口服用浓溶液与聚乙二醇电解质散结肠镜肠道准备的效果对比:基于倾向评分匹配的队列研究
- Author:
Lijun ZHENG
1
;
Tiantian GUO
1
;
Ruixiao ZHANG
1
;
Yuemei WANG
1
;
Yueying LI
1
;
Chao ZHANG
1
;
Huiyan LI
1
;
Hao XU
1
;
Qi YANG
1
Author Information
- Publication Type:Journal Article
- Keywords: magnisium sodicum potassium sulfate oral sulfate solution(OSS); polyethylene glycol(PEG)electrolytes powder; colonoscopy; bowel preparation; propensity score matching(PSM)
- From: China Journal of Endoscopy 2025;31(4):18-24
- CountryChina
- Language:Chinese
- Abstract: Objective To compare the efficacy,acceptability and safety of a low-volume magnisium sodicum potassium sulfate oral sulfate solution(OSS)with polyethylene glycol(PEG)electrolytes powder in bowel preparation for colonoscopy.Methods A prospective,single-blinded and single-center cohort study was conducted.The ambulatory and hospitalized 1 037 patients who underwent colonoscopy from April 2023 to January 2024 were enrolled.Participants were divided into OSS group(639 cases)and PEG group(398 cases),according to the bowel cleansing drugs taken orally.After propensity score matching(PSM),each group included 385 cases.The success rate of bowel preparation,scores of Boston bowel preparation scale(BBPS),medication taste,patients'satisfaction and the occurrence of adverse events were compared.Results The success rate of bowel preparation in the OSS group was 96.4％(371/385),higher than the 91.7％(353/385)in the PEG group,and the difference was statistically significant(P＜0.05).The total and segmented BBPS scores of the OSS group were higher than those of the PEG group,the differences were statistically significant(P＜0.05).The medication taste and patients satisfaction of the OSS group were significantly better than those of the PEG group,the differences were statistically significant(P＜0.05).There was no statistically significant difference in incidence of adverse reactions between the two groups(P=0.800).Conclusion Compared to PEG,OSS has a better intestinal cleaning effect,medication taste,and patients satisfaction.In addition,OSS has security that is not inferior to PEG.
