Monitoring as well as prevention and control strategies for nasal vestibular colonized bacteria of healthcare workers in pediatric intensive care unit
10.12138/j.issn.1671-9638.20252164
- VernacularTitle:儿童重症监护病房医护人员鼻前庭定植菌监测与防控策略研究
- Author:
Zixuan LI
1
;
Lili HUANG
;
Zhenjiang BAI
;
Shuiyan WU
;
Linna ZHANG
;
Zhiqin ZHANG
;
Chunmei SU
Author Information
1. 苏州大学附属儿童医院重症医学科,江苏 苏州 215025
- Publication Type:Journal Article
- Keywords:
nasal colonized bacteria;
Staphylococcus aureus;
Klebsiella spp.;
infection prevention and control;
pediatric intensive care unit
- From:
Chinese Journal of Infection Control
2025;24(10):1424-1429
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the distribution characteristics and influencing factors of nasal colonized bacteria of healthcare workers(HCWs)in pediatric intensive care unit(PICU).Methods A cross-sectional study was con-ducted.Nasal swab specimens from 104 HCWs in the PICU of a hospital were collected for bacterial culture and an-timicrobial susceptibility testing.According to the identification and antimicrobial susceptibility testing results of strains,distribution characteristics of colonized bacteria was analyzed.Basic information of studied subjects were collected through questionnaire survey,and risk factors for colonized bacterial infection were conducted using logis-tic regression analysis.Results Among 104 specimens,colonized bacteria were detected from 66 specimens,with an overall detection rate of 63.46％.Gram-positive bacteria was mainly Staphylococcus aureus,with a detection rate of 34.62％(n=36),out of which methicillin-resistant Staphylococcus aureus(MRSA)accounted for 2.88％(n=3).Gram-negative bacteria was mainly Klebsiella spp.,with a detection rate of 21.15％(n=22).Multiva-riate logistic regression analysis showed that HCWs with junior professional titles(OR=11.400,95％CI:2.329-55.801,P=0.003)was an independent risk factor for Staphylococcus aureus colonization,and male(OR=4.260,95％CI:1.160-15.653,P=0.029)was an independent risk factor for Klebsiella spp.colonization.Conclusion Nasal cavity of HCWs in PICU has a high detection rate of colonized bacteria,with Staphylococcus aureus and Klebsiella spp.being the major colonized bacteria.
