Hematopoietic stem cell transplantation 50 years
10.3760/cma.j.cn121090-20250509-00221
- VernacularTitle:造血干细胞移植50年
- Author:
Xiaojun HUANG
1
Author Information
1. 北京大学人民医院，北京大学血液病研究所，国家血液系统疾病临床医学研究中心，造血干细胞移植治疗血液病北京市重点实验室，北京 100044
- Publication Type:Journal Article
- From:
Chinese Journal of Hematology
2025;46(6):489-493
- CountryChina
- Language:Chinese
-
Abstract:
Hematopoietic stem cell transplantation (HSCT), a curative procedure for the majority of hematologic disorders, has seen remarkable development in China. In 1964, Lu Daopei performed Asia's first and the world’s fourth HSCT, marking the beginning of China’s progress in this field. Huang Xiaojun completed the world's first haploidentical HSCT without in vitro T-cell depletion in 2000. The protocol has evolved into a system named "Beijing Protocol" by the Worldwide Network for Blood and Marrow Transplantation (WBMT) in 2016, which is currently a mainstream global haploidentical transplantation protocol. The emergence of novel cellular therapies has revolutionized the conventional hematopoietic stem cell transplantation model. From learning from the west, Chinese scholars have strived to reshape the global HSCT landscape.
