The Cost-effectiveness Analysis of High-Flux Hemodialysis versus Low-flux Hemodialysis in End-stage Renal Disease Patients
- VernacularTitle:高通量血液透析对比低通量血液透析治疗终末期肾病患者的成本效果分析
- Author:
Yaoling WANG
1
;
Xin GAO
;
Xue LI
;
Feiyi XIAO
;
Yisha LIN
;
Wudong GUO
;
Kun ZHAO
Author Information
1. 国家卫生健康委卫生发展研究中心 北京 100044
- Publication Type:Journal Article
- Keywords:
end-stage renal disease;
cost-effectiveness analysis;
high-flux hemodialysis;
low-flux hemodialysis
- From:
Chinese Health Economics
2025;44(5):38-42
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the cost-effectiveness of high-flux hemodialysis compared to low-flux hemodialysis in the treat-ment of End-Stage Renal Disease(ESRD)patients.Methods:Based on a literature review,a cost-effectiveness analysis model was established,using the Incremental Cost-Effectiveness Ratio(ICER)as the outcome indicator to evaluate the economic value of high-flux versus low-flux hemodialysis.One-way sensitivity analysis and probabilistic sensitivity analysis were conducted to further assess the robustness of the results.Results:In the treatment of ESRD patients,compared to low-flux hemodialysis,the ICER of high-flux hemodialysis was 234 882 yuan per QALY.The key factors influencing the model results were the cost discount rate,ef-fect discount rate,utility value of high-flux hemodialysis,and treatment costs.Conclusion:Compared to low-flux hemodialysis,high-flux hemodialysis demonstrates a cost-effectiveness advantage at a willingness-to-pay threshold of three times GDP per capita.
