Association of histone methylation modification with cardiovascular diseases
- VernacularTitle:组蛋白甲基化修饰与心血管疾病
- Author:
Ziwei WANG
1
;
Meifei WANG
1
;
Qiqi WANG
1
;
Haopeng WANG
1
;
Rong ZHOU
1
;
Ziqiao YUAN
1
;
Wen ZHAO
1
Author Information
- Publication Type:Journal Article
- Keywords: histone methylation modification; cardiovascular diseases; atherosclerosis
- From: Chinese Journal of Arteriosclerosis 2025;33(4):286-296
- CountryChina
- Language:Chinese
- Abstract: Histone methylation modification,as one of the post-translational modifications,has been increasingly shown by studies to play a crucial role in the development of cardiovascular diseases(CVD).Due to its reversibility,tar-geting related modifying enzymes is expected to provide new strategies for the clinical diagnosis and treatment of CVD.This article reviews the relevant methylation modifications and their important regulatory mechanisms in CVD,and discusses the research progress of histone methylation inhibitors in the cardiovascular field.
