Arsenic Concentrations and Risk Assessment in Children from Low-Arsenic Exposure Areas
10.3870/j.issn.1672-0741.25.03.014
- VernacularTitle:低砷暴露地区儿童砷暴露水平及其风险评价
- Author:
Qi MAI
1
;
Jiahao LI
;
Miaomiao YAN
Author Information
1. 武汉市疾病预防控制中心公共检验检测中心,武汉 430020
- Publication Type:Journal Article
- Keywords:
arsenic species;
infants and young children;
arsenic metabolism;
low-arsenic areas;
health risk assess-ment
- From:
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
2025;54(5):672-678
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate internal arsenic exposure levels and influencing factors in infants and young children from low-arsenic regions.Methods A total of 390 urine samples from 130 children aged 0-7 years in Wuhan(central China)and Shenzhen(southern China)were analyzed using high performance liquid chromatography-inductively coupled plasma mass spec-trometry.A linear mixed model was applied to assess factors influencing arsenic exposure levels,and risk evaluation was conduc-ted based on biomonitoring equivalents.Results The average urinary total arsenic level in children was 15.6 μg/L.The concen-trations of these species increased with age,except for arsenate(AsⅤ).Children in Shenzhen had higher level of arsenobetaine(AsB)than in Wuhan(P＜0.05).The urinary levels of monomethyl arsenic acid(MMA)and dimethyl arsenic acid(DMA)were significantly higher in winter than in autumn(P＜0.05).Total urinary arsenic levels in 72％of the children exceeded the bio-monitoring equivalent.Conclusion Arsenic exposure among children shows an increasing trend with age,and there are regional and seasonal differences.More than half of the children may suffer potential health risks of As exposure,highlighting the urgent need for improved monitoring and preventive measures.
