Correlation between a body shape index and osteoporosis in postmenopausal women
10.12007/j.issn.0258-4646.2025.10.002
- VernacularTitle:身体形态指数与绝经后女性骨质疏松症的相关性
- Author:
Yingxin SHAO
1
;
Bin WU
1
Author Information
1. 中国医科大学附属第一医院全科医学科,沈阳 110001
- Publication Type:Journal Article
- Keywords:
a body shape index;
osteoporosis;
visceral fat;
postmenopause
- From:
Journal of China Medical University
2025;54(10):869-875
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between a body shape index(ABSI)and osteoporosis in postmenopausal women and evaluate its screening value.Methods The clinical data of 285 postmenopausal women were retrospectively collected.The patients were divided into the normal(n=100),osteopenia(n=102),and osteoporosis(n=85)groups based on the dual-energy X-ray absorptiometry(DXA)results,and their clinical characteristics were compared.Pearson's correlation and logistic regression analyses were performed to assess the correlation between ABSI and osteoporosis.The ABSI value for osteoporosis screening was evaluated using a receiver operating characteristic(ROC)curve.Results The ABSI value was significantly higher in the osteoporosis group than in the normal and osteopenia groups(P＜0.05),consistent with the results of the modified a body shape index for Chinese adults(CABSI)based on the body shape cha-racteristics of the Chinese population.Lumbar spine and bilateral hip bone mineral density were positively correlated with diastolic blood pressure(DBP),fasting blood glucose(FBG),triglyceride(TG),uric acid(UA),height,weight,waist circumference,and body mass index(BMI)(P＜0.05)and negatively correlated with age,high-density lipoprotein cholesterol(HDL-C),ABSI,and CABSI(P＜0.05).Logistic regression analysis revealed that the osteoporosis risk in the highest quartile groups of ABSI and CABSI was 3.084-and 3.541-fold that of the lowest quartile groups,respectively.The CABSI showed the highest sensitivity(77.1％),whereas weight exhibited the best diagnostic accuracy(area under the curve=0.691)and highest specificity(80.7％).Conclusion Elevated ABSI and CABSI scores are significantly associated with osteoporosis risk in postmenopausal women.Overall,CABSI shows a relatively high screening sensitivity and is therefore a potential indicator for early osteoporosis identification.
