Association between body temperature and duration of mechanical ventilation in ICU following CABG: based on Medical Information Mart for Intensive Care Ⅳ database
10.3760/cma.j.cn131073-20240810-00812
- VernacularTitle:CABG术后患者体温与ICU机械通气时间的关系：基于MIMIC-Ⅳ数据库
- Author:
Liang ZHAO
1
;
Jumin YAN
;
Jianjun YANG
;
Qingren LIU
;
Hongdang XU
;
Yanan LI
;
Hongqi LIN
Author Information
1. 阜外华中心血管病医院 郑州大学华中阜外医院 河南省人民医院 郑州大学人民医院麻醉与围术期医学科 河南省心血管疾病临床医学研究中心 郑州市经食管超声心动图重点实验室，郑州 450046
- Publication Type:Journal Article
- Keywords:
Coronary artery bypass;
Body temperature;
Respiration, artificial;
Intensive care units
- From:
Chinese Journal of Anesthesiology
2025;45(8):987-991
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the association between body temperature and duration of mechanical ventilation in the intensive care unit (ICU) among patients after coronary artery bypass grafting (CABG).Methods:Clinical data from patients, aged >18 yr, undergoing primary isolated CABG, between 2008 and 2019, were extracted from the Medical Information Mart for Intensive Care Ⅳ version 2.0 database. Participants were stratified into 3 groups based on the mean body temperature in ICU: hypothermia group (<36.0 ℃), normothermia group (36.0 ℃ ≤ temperature <37.3 ℃), and hyperthermia group (≥37.3 ℃). Multivariable linear regression and linear curve fitting were performed to assess the association between body temperature and duration of mechanical ventilation.Results:A total of 4, 588 patients were finally included in the statistical analysis, including 133 cases in hypothermia group, 4, 177 cases in normothermia group and 278 cases in hyperthermia group. The duration of mechanical ventilation was significantly prolonged in both hypothermia and hyperthermia groups compared with normothermia group ( P<0.05). The results of multivariable linear regression demonstrated that each 1 ℃ increase in body temperature was associated with a 2.43 h reduction in the duration of mechanical ventilation in hypothermia group ( P<0.001), and each 1 ℃ temperature elevation corresponded to a non-significant reduction of 0.12 h in hyperthermia group ( P=0.851). The results of linear curve fitting revealed a U-shaped relationship between body temperature and duration of mechanical ventilation, and an inflection point was identified at 36.71 ℃, with duration of mechanical ventilation prolonged with temperatures either below or above this threshold ( P<0.05). Conclusions:Hypothermia during ICU stay following CABG may lead to prolonged mechanical ventilation in patients.
