Efficacy analysis of Deanxit in the treatment of irritable bowel syndrome and functional dyspepsia overlap syndrome
10.3760/cma.j.issn.1009-6906.2019.02.016
- VernacularTitle:氟哌噻吨美利曲辛治疗肠易激综合征与功能性消化不良重叠征患者的疗效分析
- Author:
Jian SONG
1
;
Liya XU
1
;
Haiyang MIN
1
;
Jijing SHI
1
Author Information
1. 上海市虹口区江湾医院消化内科,上海,200434
- Publication Type:Journal Article
- Keywords:
Deanxit;
Irritable bowel syndrome;
Functional dyspepsia;
Overlap syndrome;
Efficacy
- From:
Chinese journal of nautical medicine and hyperbaric medicine
2019;26(2):143-145
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of antidepressant Deanxit in the treatment of irritable bowel syndrome (IBS) and functional dyspepsia (FD) overlap syndrome.Methods One hundred and twentyeight patients with IBS and FD overlap syndrome admitted into the Jiangwan Hospital of Hongkou District,Shanghai for medical treatment from March,2014 to December,2017 were randomly divided into the control group and the observation group,each consisting of 64 patients.The control group received pinaverium bromide and omeprazole,while the observation group was treated with Deanxit.The differences in the efficacy,the Hamilton anxiety rating scale(HAMA) and the Hamilton depression rating scale (HAMD) were compared and analyzed between the patients of the 2 groups.Results Total effective rate of the observation group was 96.7％,which was significantly higher than that of the control group,and statistical significance could be seen when comparisons were made between the 2 groups (P ＜ 0.01).After intervention,both the HAMD and HAMA scores in the observation group decreased notably and were significantly lower than those in the control group,with statistical significance (P ＜ 0.01).Conclusion Deanxit could achieve sure results in the treatment of IBS and FD overlap syndrome,effectively improve clinical symptoms and relieve anxiety or depression.Therefore,it is worth clinical promotion.
