Comparison of the effects of peripheral with transcranial magnetic stimulation in the treatment of functional constipation
10.3760/cma.j.cn421666-20240417-00286
- VernacularTitle:外周与中枢重复经颅磁刺激治疗功能性便秘的疗效对比
- Author:
Haoyuan XIE
1
;
Jun CHEN
1
Author Information
1. 陕西中医药大学，咸阳 712046
- Publication Type:Journal Article
- Keywords:
Constipation;
Transcranial magnetic stimulation;
Peripheral magnetic stimulation;
Lactulose
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2025;47(2):123-126
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the efficacy of peripheral and central transcranial magnetic stimulation (rTMS) in the treatment of functional constipation.Methods:Sixty patients with functional constipation were randomly divided into a control group, a peripheral group and a central group, each of 20. All were given oral lactulose medication, while the peripheral groups was additionally provided with high-frequency repetitive magnetic stimulation (rMS) treatment in the sacral region (S2-4) and the central group received low-frequency rTMS treatment in the right dorsal prefrontal cortex. Before and after 3 weeks of treatment, all were evaluated in terms of the average weekly frequency of spontaneous complete bowel movements (SCBM), major constipation symptom scoring, and using the Constipation Patient Symptom Self Rating Scale (PAC-SYM).Results:After the treatment, all of the indicators had improved significantly in all three groups, but all were better in the peripheral and central groups than in the control group, on average. The peripheral group and the central group averages were not significantly different after the treatment. The total effectiveness rates in the peripheral and central groups both exceeded 90%, significantly better than among the control group.Conclusions:Both peripheral high-frequency rTMS and central low-frequency rTMS can effectively supplement lactulose drug treatment in relieving the symptoms of constipation.
